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Řemeslník tvar hrozit overall mutation load and p53 mutations nebezpečný poškrábat halda

Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | Nature Communications
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | Nature Communications

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

Rare Mutation of TP53 Gene Leaves People at Higher Risk for Multiple Cancers - Penn Medicine
Rare Mutation of TP53 Gene Leaves People at Higher Risk for Multiple Cancers - Penn Medicine

Scientists unveil chemotherapy resistance mechanism related to p53 mutation
Scientists unveil chemotherapy resistance mechanism related to p53 mutation

Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram

Development of TP53 mutations over the course of therapy for acute myeloid leukemia - Alwash - 2021 - American Journal of Hematology - Wiley Online Library
Development of TP53 mutations over the course of therapy for acute myeloid leukemia - Alwash - 2021 - American Journal of Hematology - Wiley Online Library

IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?

Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM

Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway
Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway

Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes
Cancers | Free Full-Text | TP53 Combined Phenotype Score Is Associated with the Clinical Outcome of TP53-Mutated Myelodysplastic Syndromes

An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation | Science Advances
An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation | Science Advances

Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics

Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram
Survival of patients with p53 mutations in the DNA-binding motifs... | Download Scientific Diagram

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden | Genome Medicine | Full Text
Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden | Genome Medicine | Full Text

Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway: Cell
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway: Cell

TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram

The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics
The p53 network: cellular and systemic DNA damage responses in cancer and aging: Trends in Genetics

TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Recurrent somatic mutations reveal new insights into consequences of mutagenic processes in cancer | PLOS Computational Biology
Recurrent somatic mutations reveal new insights into consequences of mutagenic processes in cancer | PLOS Computational Biology

Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis | Cell Death Discovery

Clinical implications of subclonal TP53 mutations in acute myeloid leukemia | Haematologica
Clinical implications of subclonal TP53 mutations in acute myeloid leukemia | Haematologica

The function of a heterozygous p53 mutation in a Li-Fraumeni syndrome patient | PLOS ONE
The function of a heterozygous p53 mutation in a Li-Fraumeni syndrome patient | PLOS ONE

Recent findings on molecular alterations in IDH1, TP53, and CASP9 in gliomagenesis | Biomedical Research and Therapy
Recent findings on molecular alterations in IDH1, TP53, and CASP9 in gliomagenesis | Biomedical Research and Therapy

Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies
Frontiers | Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

Significance of TP53 mutation in bladder cancer disease progression and drug selection [PeerJ]
Significance of TP53 mutation in bladder cancer disease progression and drug selection [PeerJ]