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Artificial Intelligence in Drug Design—The Storm Before the Calm? | ACS Medicinal Chemistry Letters
Artificial Intelligence in Drug Design—The Storm Before the Calm? | ACS Medicinal Chemistry Letters

Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors | ACS Medicinal Chemistry Letters
Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors | ACS Medicinal Chemistry Letters

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Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35 | ACS Medicinal Chemistry Letters
Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35 | ACS Medicinal Chemistry Letters

Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition | ACS Medicinal Chemistry Letters
Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition | ACS Medicinal Chemistry Letters

Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists | ACS Medicinal Chemistry Letters
Discovery of Heteroaryl Urea Isosteres for Formyl Peptide Receptor 2 Agonists | ACS Medicinal Chemistry Letters

ACS Med Chem Lett (@ACSMedChemLett) / Twitter
ACS Med Chem Lett (@ACSMedChemLett) / Twitter

Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C | ACS Medicinal Chemistry Letters
Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C | ACS Medicinal Chemistry Letters

ACS Med Chem Lett (@ACSMedChemLett) / Twitter
ACS Med Chem Lett (@ACSMedChemLett) / Twitter

ACS Medicinal Chemistry Letters: Volume 11, Issue 5
ACS Medicinal Chemistry Letters: Volume 11, Issue 5

Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice | ACS Medicinal Chemistry Letters
Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice | ACS Medicinal Chemistry Letters

Discovery of Potent Deuterated Compounds as Potential KRASG12D Inhibitors in Cancer Therapy | ACS Medicinal Chemistry Letters
Discovery of Potent Deuterated Compounds as Potential KRASG12D Inhibitors in Cancer Therapy | ACS Medicinal Chemistry Letters

Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules | ACS Medicinal Chemistry Letters
Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules | ACS Medicinal Chemistry Letters

Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC Design | ACS Medicinal Chemistry Letters
Phenyl Dihydrouracil: An Alternative Cereblon Binder for PROTAC Design | ACS Medicinal Chemistry Letters

Novel Reagent Space: Identifying Unorderable but Readily Synthesizable Building Blocks | ACS Medicinal Chemistry Letters
Novel Reagent Space: Identifying Unorderable but Readily Synthesizable Building Blocks | ACS Medicinal Chemistry Letters

Readily Accessible High-Throughput Experimentation: A General Protocol for the Preparation of ChemBeads and EnzyBeads | ACS Medicinal Chemistry Letters
Readily Accessible High-Throughput Experimentation: A General Protocol for the Preparation of ChemBeads and EnzyBeads | ACS Medicinal Chemistry Letters

Scaffold-Hopping of Aurones: 2-Arylideneimidazo[1,2-a]pyridinones as Topoisomerase IIα-Inhibiting Anticancer Agents | ACS Medicinal Chemistry Letters
Scaffold-Hopping of Aurones: 2-Arylideneimidazo[1,2-a]pyridinones as Topoisomerase IIα-Inhibiting Anticancer Agents | ACS Medicinal Chemistry Letters

Discovery and Development of Cyclic Peptide Inhibitors of CIB1 | ACS Medicinal Chemistry Letters
Discovery and Development of Cyclic Peptide Inhibitors of CIB1 | ACS Medicinal Chemistry Letters

ACS Medicinal Chemistry Letters | Ahead of Print
ACS Medicinal Chemistry Letters | Ahead of Print

Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation | ACS Medicinal Chemistry Letters
Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation | ACS Medicinal Chemistry Letters

Design, Synthesis, and Anti-HBV Activity of New Bis(l-amino acid) Ester Tenofovir Prodrugs | ACS Medicinal Chemistry Letters
Design, Synthesis, and Anti-HBV Activity of New Bis(l-amino acid) Ester Tenofovir Prodrugs | ACS Medicinal Chemistry Letters